Bagnaia’s bid to convert another pole into victory and become the third rider to win five consecutive MotoGP races was helped by a brilliant start as he led teammate Jack Miller into the first corner.
However, the best start came from Marquez as the Honda rider moved from 13th to sixth on the exit of the first corner.
That was until utter chaos guaranteed three turns later…
Marquez had a great moment on the exit of the fourth corner, which allowed Quartararo to run straight into the Repsol Honda rider – shades of Valentino Rossi when he met Jorge Lorenzo a few years ago in Assen.
But with nowhere to go due to Marquez’s proximity – the contact between the two riders had a much more damaging effect this time around as the reigning world champion crashed out before Marquez had a another drama three corners later.
Slowly exiting turn seven with the rear of his RC213V heavily damaged, Marquez unintentionally collided with Takaaki Nakagami who was on the outside, resulting in a very frightening crash for the Japanese driver.
Nakagami fell immediately before being almost hit by several runners – luckily he was not picked up by anyone.
Eager to make progress as race leader Bagnaia pulled away from Miller, Enea Bastianini made the move on lap seven.
The future Ducati factory rider then began to close in on Bagnaia as a repeat of their Misano battle seemed to be on the cards.
But unlike Misano, Bastianini was able to get ahead of Bagnaia by making light work of the Italian a lap later.
A brilliant move into corner one was then followed by Bastianini who ran wide at turn 13, restoring the lead to Bagnaia.
After nearly losing a second to Bagnaia, Bastianini started a new charge, closing within half a second.
Third, Binder was starting to get away from Aleix Espargaro and Miller after surviving their first pressure.
As the laps began to tick away, Bastianini’s second wind saw him nearly three-tenths off Bagnaia, while Binder again came under pressure from Espargaro.
With two laps to go, Espargaro made a sensational move over Binder to take third, a position he held until the checkered flag, while Bastianini did the same with Bagnaia for the win at turn seven in the last round.
Bagnaia could not respond as he instead took second place and moved within ten points of Quartararo in the championship standings.